News 2019 and Earlier
Nov 21, 2019
Organs are 3D & our analysis of pathology should be too. So we developed DUCT to visualize and quantify the 3D architecture of the murine liver vascular and biliary systems. – leading to new discoveries in Alagille syndrome. This work, led by Simona Hankeova, is now in bioRxiv!
June 14, 2019
Simona Hankeova, our first PhD student, succesfully defends her PhD! With excellent opposition and discussion from Dr Rui Benedito. Congratulations Dr Hankeova!
May 28, 2019
April 10-14, 2019
Emma was elected the Scientific Committee of the EASL Governing Board. EASL brings together over 4,000 members, organizes a yearly meeting for over 9,000 attendees and aims “spread knowledge and expertise in best practices and the latest scientific breakthroughs in hepatology”, through education, conferences and more.
This year, Jan Masek, post doc, presented his ongoing and planned work as part of the Sheila Sherlock post doctoral fellowship he received.
Emma chaired sessions on “Automimmune and cholestatic liver disease”, and “Clinical developments in rare liver disease.”
Emma also gave a talk on the “Challenges women face in academia”, which you can view here, or below.
All in all, a very exciting meeting, presenting new developments in basic, clinical and translational research.
March 1st, 2019
Registration to The Notch Meeting 2019 in Athens Oct 6-10, co-organized by Emma, is open now! Please register to guarantee a spot at this vibrant meeting! Lovely poster featuring blood vessels imaged by Simona Hankeova, PhD student in the lab.
March 1, 2019
Feb 11, 2019
We welcome our new PhD student Sandra de Haan to the lab!
Our book chapter on Future Therapeutic Approaches for Alagille Syndrome is published. This book, with chapters from leaders in the field of Alagille syndrome, spanning liver pathology to bone defects, was edited by Binita Kamath and Kathy Loomes.
Welcome to our new postdoc, Emine Ezel Cilek!
Emma attends the exciting Gordon Research Conference on Notch Signaling in Development, Regeneration and Disease as discussion leader. Lots of great talks, wonderful colleagues and a flash flood to boot.
Emma has been working as Guest Editor on a special issue in Developmental Biology on the Blueprint for life… The focus is signaling pathways in development, spanning different model organisms and concepts from ligand dispersal to lateral inhibition and autophagy. The Editorial Introduction, written with Jeffrey Bush from UCSF is published – looking forward to the full issue being ready soon!
Emma presents some of our work on Notch in liver cancer at the The 8th International Conference on Notch Targeting in Cancer.
Congratulations David Kosek on a successful registration seminar and welcome as our newest PhD student!
Today Jan Masek, post doc in our lab, recieved the prestigious EASL (European Association for the Study of the Liver) Sheila Sherlock post doctoral fellowship at the International Liver Congress! Congratulations again Janek! It was a great conference, and we struck up lots of new great collaborations!
Noemi van Hul joins our lab in a Senior Scientist type of position. -Welcome Noemi!
Congratulations Jan Masek, post doc in our lab, on being awarded the prestigious EASL (European Association for the Study of the Liver) Sheila Sherlock post doctoral fellowship! This internationally competitive post doc grant is awarded to two-three fellows in Europe each year.
Jingyan He is officially registered as a PhD student in our lab at the Department of Cell and Molecular Biology at Karolinska Institutet. Congratulations, and welcome!
Our open access Gastroenterology paper is finally out! In this paper, we describe a novel model for Alagille syndrome, which we then compare with human liver samples from patients with Alagille syndrome. By cross-referencing with the Human Protein Atlas, we identify novel markers of bile ducts and show that the apical side of bile ducts is specifically disrupted. Finally, we show that the missense mutation driving the Alagille phenotype in the mouse model is Notch receptor selective – a completely novel finding with implications for ligand-receptor specificity.
Thanks to the Swedish Research Council/Vetenskapsrådet (VR) for continuing to support our 3R research.
The Swedish Heart and Lung Foundation (Hjärt-Lungfonden) has awarded the Andersson Lab a grant to study Notch signaling and stroke, focused on Alagille syndrome. Thank you to the Foundation, and the donors, for your meaningful support.
Marika Sjöqvist and Emma Andersson’s review on Lateral patterning cues is accepted in Developmental Biology!
Emma gave a talk at Children’s Hospital of Philadelphia, with Kathy Loomes as host.
Emma presents at the University of Hartford Neuroscience Symposium
Congratulations Afshan Iqbal on your PhD studies registration seminar! An intercontinental challenge, with Afshan presenting to the Doctoral Admissions board at Karolinska/BioNut, and Emma joining from New Haven over Skype, at 4am. All went well, and we are delighted to welcome our most recent official lab member!
Our review is out! Read about Congenital Notch disorders and how Notch controls embryonic development in the May issue of Development.
Emma R Andersson is awarded the EASL Daniel Alagille Award! This award is given to one person in Europe under 40 for a groundbreaking project in genetic cholestatic liver disease.
Jan Mašek (with Andersson Lab as applicant) is awarded a post doc grant from the Wenner Gren Foundation! We congratulate Janek and thank the foundation for their support!
Katja Petzold (as main PI) and Emma R Andersson are awarded a grant from Knut and Alice Wallenberg’s foundation! This generous grant will allow us to build up a team and continue our collaboration investigating the role of miR structure in vivo, using ultaround-guided nanoinjection of the nervous system. For more info see http://ki.se/en/news/four-projects-to-share-143-million-from-knut-and-alice-wallenberg-foundation, https://www.wallenberg.com/kaw/sma-molekyler-styr-hjarnans-utveckling-och-cancer
Welcome to our new Post Doc Jan Mašek!
Congratulations Bettina Semsch on your promotion to Animal Technician Specialist!
Emma receives one of the competitive Assistant Professor Funding positions from Karolinska Institutet (262 applicants, 7 awarded funding, 2.7% success rate).
The Sven and Ebba-Christina Hagberg prize in medicine 2014 is awarded to Emma Andersson, Senior researcher at the Department of Biosciences and Robert Månsson, Assistant professor at the Department of Laboratory Medicine.