Emma R Andersson, Principle Investigator
Dr Emma R. Andersson is a Principle Investigator running a lab with two sites, one at the Department of Cell and Molecular Biology at the Karolinska Institutet, and one at the South campus of the Karolinska University hospital. As a Ph.D. student with Ernest Arenas at the department of Medical Biochemistry and Biophysics (MBB) at Karolinska Institutet, she elucidated several roles for Wnt signaling in the morphogenesis and differentiation of the embryonic midbrain. After defending her PhD in 2009, she pursued postdoctoral studies with Urban Lendahl at the department of Cell and Molecular Biology (CMB), also at Karolinska Institutet, where her work focused on the role of Notch signaling in development and disease of the nervous system and in the liver. In order to devise a method to rapidly manipulate gene expression in the developing embryonic nervous system and other organ systems, she performed guest research in the laboratories of Professors Elaine Fuchs and Mary E Hatten (Rockefeller University, New York, USA) to further develop the technique of ultrasound-guided in utero microinjection of lentivirus. This technique was originally developed to target developing skin, but the Andersson lab has now established protocols which allow targeting of several organ systems during development, including the nervous, gastric and respiratory systems. She has established the technology as a core facility (Infinigene: Infrastructure for ultrasound-guided in utero injection and rapid genetic manipulation in mouse), in addition to a core facility for virus production. Full CV.