Andersson Lab — Developmental Biology & Regeneration
We uncover how organ systems acquire correct cellular identities and architecture, and why mutations cause congenital disease.
We build in utero genetic tools (NEPTUNE), use 3D cultures, and employ large-scale single-cell and spatial omics to study development and regeneration, with a focus on genetic disease.
Highlights
In utero genetics
de Haan & He et al. (2025). Our technology NEPTUNE enables in vivo barcode delivery, yielding high-resolution clonal maps of development of the CNS and auditory system.
Alagille syndrome & Notch genetics
We work to resolve why and how Notch dysregulation affects multiple organ systems, including the liver, vasculature and hearing.
Principles of miRNA–mRNA targeting
We define structural rules for microRNA–mRNA pairing beyond the seed and Argonaute-tuned repression strength across targets.
Crocodiles, regeneration and hearing
Emma, Helge and Lena discuss cross-species sensory-organ regeneration and how its principles could be used to restore hearing in mammals.
Göran Gustafsson Prize in Medicine 2026
“For the development of innovative methodology for basic and translational studies of early embryonic development.”
ERC Consolidator Grant: LIMITLESS
A five-year programme to develop whole-organism genetic manipulation through in utero nano-injection.